Home Order Product Contact Us Our Policies Breast Health Info Prostate Health Info Diabetes Info Heart Health Info Lignan Research & Links Bulk Product Info Testimonials

Premium Flaxseed Lignan Extract over 80 times more powerful than flaxseed oil.

Lignan Research & Links

Prostate Cancer and Lignans

Diabetes and Lignans

Heart Disease and Lignans

Lignans have numerous biological properties that make them unique & very useful in promoting health and combating various diseases.  Since the early 1980s, lignans have come under increasing scientific scrutiny after studies suggest that they may prevent the development of breast, prostate, colon & other cancers.  Additional research has shown that they may prevent many types of coronary heart disease and diabetes. With cancer now striking one in three Americans, it seems that lignans' greatest gift to man is their well-documented anti-cancer activity. Research has shown that people who excrete high amounts of lignans in their urine (indicative of a high intake) have markedly lower cancer rates.
**Adlercreutz, H., Mazur, W., "Phyto-estrogens and Western Diseases," Ann. Med., 1997, 29(2): 95-120.
Additional Research Articles Regarding Flaxseed Lignans:
1. Lin X, et al. Effect of mammalian lignans on the growth of prostate cancer cell lines. Anticancer Research. 21:3995-99, 2001.
2. Ranich T, et al. Protective effects of dietary phytoestrogens in chronic renal disease. J Renal Nutrition 2001 Oct; 11(4): 183-93.
3. Thompson LU. Experimental studies on lignans and cancer. Baillieres Clin Endocrin Metab. 12:691-705, 1998.
4. Hirano T, et al. Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer Investigation 1990; 8(6): 595-602.
5. Denmark-Wahnefried W, et al. Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. Urology. 58:47-52, 2001.
6. Serraino M, et al. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Letters. 60(1991) 135-142.
7. Haggans CJ, et al. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutrition and Cancer. 33:188-195, 1999.
8. Tham DM, et al. Potential health benefits of dietary phytoestrogens: A review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab. 83: 2223-2235, 1998.
9. Sung MK, et al. Mammalian lignans inhibit the growth of estrogen independent human colon cancer cells. Anticancer Research. 18: 1405-8, 1998
10. Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglycoside isolated from flaxseed. Circulation. 99:1355-1362, 1999.
11. Prasad K, et al. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis. 136: 367-375, 1998.
12. Nesbitt PD, et al. Human metabolism of mammalian lignan precursors in raw and processed flaxseed. Amer J Clin Nutr. 69: 549-555, 1999.
13. Thompson LU, et al. Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 1996 Jun; 17(6):1373-6.
14. Sung MK, et al. Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. Anticancer Research 1998; 18: 1405-1408.

Useful Links

These links may be useful resources to conduct your own research on flaxseed lignans:

The National Library of Medicine website. On this site, you can type in keywords of topics you would like to research.


Useful link that outlines information regarding flaxseed lignans.

PMAP Conference Details

A great resource for medical information on the Internet.


Green Leaf Products, Inc.