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Additional Research Articles Regarding Flaxseed Lignans:
1. Lin X, et al. Effect of mammalian lignans on the growth
of prostate cancer cell lines. Anticancer Research. 21:3995-99, 2001.
2. Ranich T, et al. Protective effects of dietary phytoestrogens
in chronic renal disease. J Renal Nutrition 2001 Oct; 11(4): 183-93.
3. Thompson LU. Experimental studies on lignans and cancer.
Baillieres Clin Endocrin Metab. 12:691-705, 1998.
4. Hirano T, et al. Antiproliferative activity of mammalian
lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer Investigation 1990; 8(6): 595-602.
5. Denmark-Wahnefried W, et al. Pilot study of dietary
fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal
levels, prostate-specific antigen, and histopathologic features. Urology. 58:47-52, 2001.
6. Serraino M, et al. The effect of flaxseed supplementation
on early risk markers for mammary carcinogenesis. Cancer Letters. 60(1991) 135-142.
7. Haggans CJ, et al. Effect of flaxseed consumption on
urinary estrogen metabolites in postmenopausal women. Nutrition and Cancer. 33:188-195, 1999.
8. Tham DM, et al. Potential health benefits of dietary
phytoestrogens: A review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab. 83: 2223-2235,
9. Sung MK, et al. Mammalian lignans inhibit the growth of estrogen independent human colon cancer
cells. Anticancer Research. 18: 1405-8, 1998
10. Prasad K. Reduction of serum cholesterol and hypercholesterolemic
atherosclerosis in rabbits by secoisolariciresinol diglycoside isolated from flaxseed. Circulation. 99:1355-1362, 1999.
11. Prasad K, et al. Reduction of hypercholesterolemic
atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis. 136: 367-375, 1998.
12. Nesbitt PD, et al. Human metabolism of mammalian lignan
precursors in raw and processed flaxseed. Amer J Clin Nutr. 69: 549-555, 1999.
13. Thompson LU, et al. Flaxseed and its lignan and oil
components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 1996 Jun; 17(6):1373-6.
14. Sung MK, et al. Mammalian lignans inhibit the growth
of estrogen-independent human colon tumor cells. Anticancer Research 1998; 18: 1405-1408.